Protection of Wild-Type and Severe Combined Immunodeficiency Mice against an Intranasal Challenge by Passive Immunization with Monoclonal Antibodies to the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein

Monoclonal antibodies (MAbs) to the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP) were characterized for their ability to neutralize the infectivity of this organism in vitro and in vivo. One of the MAbs (MoPn-23) recognizes a nonlinear epitope in the MOMP, MAb M...

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Hlavní autoři: Pal, Sukumar, Bravo, Jose, Peterson, Ellena M., de la Maza, Luis M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583570/
https://ncbi.nlm.nih.gov/pubmed/18809664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00574-08
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