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Orally Administered Mycobacterium vaccae Modulates Expression of Immunoregulatory Molecules in BALB/c Mice with Pulmonary Tuberculosis

The environmental saprophyte Mycobacterium vaccae induces a Th1 response and cytotoxic T cells that recognize M. tuberculosis, and by subcutaneous injection, it is therapeutic for pulmonary tuberculosis (TB) induced by high-dose challenge in BALB/c mice. However, M. vaccae also drives regulatory T c...

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Detalhes bibliográficos
Main Authors: Hernández-Pando, Rogelio, Aguilar, Diana, Orozco, Hector, Cortez, Yuriria, Brunet, Laura Rosa, Rook, Graham A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583530/
https://ncbi.nlm.nih.gov/pubmed/18827195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00286-08
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