Phase I Study of a Herpes Simplex Virus Type 2 (HSV-2) DNA Vaccine Administered to Healthy, HSV-2-Seronegative Adults by a Needle-Free Injection System

We conducted a double-blind, vehicle-controlled, dose escalation safety and immunogenicity trial of a candidate herpes simplex virus type 2 (HSV-2) surface glycoprotein D2 (gD2) DNA vaccine administered by use of a needle-free device. Sixty-two healthy adults were randomized using a 4:1 vaccine-to-p...

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Detalhes bibliográficos
Main Authors: Cattamanchi, Ashok, Posavad, Christine M., Wald, Anna, Baine, Yaela, Moses, Jennifer, Higgins, Terry J., Ginsberg, Richard, Ciccarelli, Richard, Corey, Lawrence, Koelle, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583522/
https://ncbi.nlm.nih.gov/pubmed/18784341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00167-08
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