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Cholesterol reduction by methyl-β-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells

Opioid receptors have been shown to be located in and regulated by lipid rafts/caveolae in caveolin-rich non-neuronal cells. Here, we found that caveolin-1 level was very low in rat brain and undetectable in NG108-15 cells, which endogenously express delta opioid receptors (DOR). Rat caudate putamen...

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Detalhes bibliográficos
Main Authors: Huang, Peng, Xu, Wei, Yoon, Su-In, Chen, Chongguang, Chong, Parkson Lee-Gau, Liu-Chen, Lee-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583444/
https://ncbi.nlm.nih.gov/pubmed/17141202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2006.10.032
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