Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides
Chimeric RNA/DNA oligonucleotides (“chimeraplasts”) have been shown to induce single base alterations in genomic DNA both in vitro and in vivo. The mdx mouse strain has a point mutation in the dystrophin gene, the consequence of which is a muscular dystrophy resulting from deficiency of the dystroph...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.10.5363 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|