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Effects of Cyclic Mechanical Stretch on Extracellular Matrix Synthesis by Human Scleral Fibroblasts

In order to understand the effect of mechanical strain on scleral extracellular matrix remodeling, human scleral fibroblasts were subjected to equibiaxial stretch in vitro and the expression of proteoglycans, metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase-2 (TIMP-2) were evaluat...

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Bibliographic Details
Main Authors: Shelton, Lilian, Rada, Jody Summers
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583333/
https://ncbi.nlm.nih.gov/pubmed/17123515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2006.10.004
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