The Structure of FSTL3·Activin A Complex: DIFFERENTIAL BINDING OF N-TERMINAL DOMAINS INFLUENCES FOLLISTATIN-TYPE ANTAGONIST SPECIFICITY

Transforming growth factor β family ligands are neutralized by a number of structurally divergent antagonists. Follistatin-type antagonists, which include splice variants of follistatin (FS288 and FS315) and follistatin-like 3 (FSTL3), have high affinity for activin A but differ in their affinity fo...

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Detalhes bibliográficos
Main Authors: Stamler, Robin, Keutmann, Henry T., Sidis, Yisrael, Kattamuri, Chandramohan, Schneyer, Alan, Thompson, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583307/
https://ncbi.nlm.nih.gov/pubmed/18768470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801266200
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