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Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X(5.1) receptors

Several zebrafish P2X receptors (zP2X(1), zP2X(2), and zP2X(5.1)) have been reported to produce little or no current although their mammalian orthologs produce functional homomeric receptors. We isolated new cDNA clones for these P2X receptors that revealed sequence variations in each. The new varia...

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Autori principali: Low, Sean E., Kuwada, John Y., Hume, Richard I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583207/
https://ncbi.nlm.nih.gov/pubmed/18850305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-008-9124-0
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