A bactericidal monoclonal antibody specific for the lipooligosaccharide of Bordetella pertussis reduces colonization of the respiratory tract of mice after aerosol infection with B. pertussis.

A mouse immunoglobulin G3 monoclonal antibody specific for the core oligosaccharide moiety of the lipooligosaccharide (LOS) of Bordetella pertussis has been shown to have complement-dependent bactericidal activity. This monoclonal antibody exhibits bactericidal activity against strains of B. pertuss...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Mountzouros, K T, Kimura, A, Cowell, J L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1452367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.12.5316-5318.1992
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