RANKL Inhibition Through Osteoprotegerin Blocks Bone Loss in Experimental Periodontitis

BACKGROUND: Prevention of alveolar bone destruction is a clinical challenge in periodontal disease treatment. The receptor activator of nuclear factor-kappa B ligand (RANKL) inhibitor osteoprotegerin (OPG) inhibits osteoclastogenesis and suppresses bone resorption. METHODS: To study the effects of R...

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Autori principali: Jin, Qiming, Cirelli, Joni A., Park, Chan Ho, Sugai, James V., Taba, Mario, Kostenuik, Paul J., Giannobile, William V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583091/
https://ncbi.nlm.nih.gov/pubmed/17608585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1902/jop.2007.070073
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