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Runx Expression Is Mitogenic and Mutually Linked to Wnt Activity in Blastula-Stage Sea Urchin Embryos

BACKGROUND: The Runt homology domain (Runx) defines a metazoan family of sequence-specific transcriptional regulatory proteins that are critical for animal development and causally associated with a variety of mammalian cancers. The sea urchin Runx gene SpRunt-1 is expressed throughout the blastula...

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Autores principales: Robertson, Anthony J., Coluccio, Alison, Knowlton, Peter, Dickey-Sims, Carrie, Coffman, James A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582955/
https://ncbi.nlm.nih.gov/pubmed/19020668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003770
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