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Transcriptional Responses to Estrogen and Progesterone in Mammary Gland Identify Networks Regulating p53 Activity

Estrogen and progestins are essential for mammary growth and differentiation but also enhance the activity of the p53 tumor suppressor protein in the mammary epithelium. However, the pathways by which these hormones regulate p53 activity are unknown. Microarrays were used to profile the transcriptio...

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Autors principals: Lu, Shaolei, Becker, Klaus A., Hagen, Mary J., Yan, Haoheng, Roberts, Amy L., Mathews, Lesley A., Schneider, Sallie S., Siegelmann, Hava T., MacBeth, Kyle J., Tirrell, Stephen M., Blanchard, Jeffrey L., Jerry, D. Joseph
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582927/
https://ncbi.nlm.nih.gov/pubmed/18556351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0035
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