Regulation of intestinal guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) and protein kinase C.

The heat-stable enterotoxin of Escherichia coli (STa) stimulates membrane-bound guanylate cyclase in intestinal epithelium and induces fluid and ion secretion. Using the T84 human colon carcinoma cell line as a model, we observed that phorbol esters markedly enhanced STa-stimulated cyclic GMP accumu...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Crane, J K, Wehner, M S, Bolen, E J, Sando, J J, Linden, J, Guerrant, R L, Sears, C L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1360449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.12.5004-5012.1992
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