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IL-15 as memory T-cell adjuvant for topical HIV-1 DermaVir vaccine

IL-7 and IL-15 are key cytokines involved in the generation and maintenance of memory CD8(+) T-cells. We evaluated these cytokines as molecular adjuvants for topical HIV-1 DermaVir vaccine. We found that mice receiving DermaVir formulated with HIV-1 Gag plasmid in the presence of IL-7- or IL-15-enco...

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Main Authors: Calarota, Sandra A., Dai, Anlan, Trocio, Jeffrey N., Weiner, David B., Lori, Franco, Lisziewicz, Julianna
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582635/
https://ncbi.nlm.nih.gov/pubmed/18462844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.03.067
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