Delivery of steric block morpholino oligomers by (R-X-R)(4) peptides: structure–activity studies

Redirecting the splicing machinery through the hybridization of high affinity, RNase H- incompetent oligonucleotide analogs such as phosphoramidate morpholino oligonucleotides (PMO) might lead to important clinical applications. Chemical conjugation of PMO to arginine-rich cell penetrating peptides...

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Detalhes bibliográficos
Main Authors: Abes, Rachida, Moulton, Hong M., Clair, Philippe, Yang, Sung-Tae, Abes, Said, Melikov, Kamran, Prevot, Paul, Youngblood, Derek S., Iversen, Patrick L., Chernomordik, Leonid V., Lebleu, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582615/
https://ncbi.nlm.nih.gov/pubmed/18796528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn541
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