Stearoyl-Coenzyme A Desaturase 1 Gene Expression Increases after Pioglitazone Treatment and Is Associated with Peroxisomal Proliferator-Activated Receptor-γ Responsiveness

Context and Objective: Stearoyl-coenzyme A desaturase (SCD1) is the rate-limiting enzyme that converts palmitoyl- and stearoyl-coenzyme A to palmitoleoyl- and oleoyl-cownzyme A, respectively. SCD-deficient mice are protected from obesity, and the ob/ob mouse has high levels of SCD. This study was de...

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Autors principals: Yao-Borengasser, Aiwei, Rassouli, Negah, Varma, Vijayalakshmi, Bodles, Angela M., Rasouli, Neda, Unal, Resat, Phanavanh, Bounleut, Ranganathan, Gouri, McGehee, Robert E., Kern, Philip A.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582575/
https://ncbi.nlm.nih.gov/pubmed/18697866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0782
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