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Converse Regulatory Functions of Estrogen Receptor-α and -β Subtypes Expressed in Hypothalamic Gonadotropin-Releasing Hormone Neurons

Estradiol (E(2)) acts as a potent feedback molecule between the ovary and hypothalamic GnRH neurons, and exerts both positive and negative regulatory actions on GnRH synthesis and secretion. However, the extent to which these actions are mediated by estrogen receptors (ERs) expressed in GnRH neurons...

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Главные авторы: Hu, Lian, Gustofson, Robert L., Feng, Hao, Ki Leung, Po, Mores, Nadia, Krsmanovic, Lazar Z., Catt, Kevin J.
Формат: Artigo
Язык:Inglês
Опубликовано: The Endocrine Society 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582533/
https://ncbi.nlm.nih.gov/pubmed/18701637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0192
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