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Enhancement of Protein Sensitivity for MALDI Imaging Mass Spectrometry after Chemical Treatment of Tissue Sections

MALDI Imaging Mass Spectrometry (IMS) has become a valuable tool for the investigation of the content and distribution of molecular species in tissue specimens. Numerous methodological improvements have been made to optimize tissue section preparation and matrix deposition protocols, as well as MS d...

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Detalhes bibliográficos
Main Authors: Seeley, Erin H., Oppenheimer, Stacey R., Mi, Deming, Chaurand, Pierre, Caprioli, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582528/
https://ncbi.nlm.nih.gov/pubmed/18472274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2008.03.016
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