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An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2

The Aurora B kinase is the enzymatic core of the chromosomal passenger complex, which is a critical regulator of mitosis. To identify novel regulators of Aurora B, we performed a genome-wide screen for suppressors of a temperature-sensitive lethal allele of the C. elegans Aurora B kinase AIR-2. This...

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Hlavní autoři: Heallen, Todd R., Adams, Henry P., Furuta, Tokiko, Verbrugghe, Koen J., Schumacher, Jill M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582393/
https://ncbi.nlm.nih.gov/pubmed/18854144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.08.005
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