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Pyrrole-2-Carboxylic Acid as a Ligand for the Cu-Catalyzed Reactions of Primary Anilines with Aryl Halides

[Image: see text] Pyrrole 2-carboxylic acid (L5) was found to be an effective ligand for the Cu-catalyzed mono-arylation of anilines with aryl iodides and bromides. Under the reported conditions (10% CuI/20% L5/DMSO/K(3)PO(4)/80–100 °C/20–24 h), a variety of useful functional groups were tolerated,...

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Detalhes bibliográficos
Main Authors: Altman, Ryan A., Anderson, Kevin W., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582381/
https://ncbi.nlm.nih.gov/pubmed/18543973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo8008676
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