Loss of the Ca(2+)/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine

The persistent nature of addiction has been associated with activity-induced plasticity of neurons within the striatum and nucleus accumbens (NAc). To identify the molecular processes leading to these adaptations, we performed Cre/loxP-mediated genetic ablations of two key regulators of gene express...

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Détails bibliographiques
Auteurs principaux: Bilbao, Ainhoa, Parkitna, Jan Rodriguez, Engblom, David, Perreau-Lenz, Stéphanie, Sanchis-Segura, Carles, Schneider, Miriam, Konopka, Witold, Westphal, Magdalena, Breen, Gerome, Desrivieres, Sylvane, Klugmann, Matthias, Guindalini, Camila, Vallada, Homero, Laranjeira, Ronaldo, de Fonseca, Fernando Rodriguez, Schumann, Gunter, Schütz, Günther, Spanagel, Rainer
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582267/
https://ncbi.nlm.nih.gov/pubmed/19001277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803959105
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