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The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene
Parafibromin is a tumor suppressor protein encoded by HRPT2, a gene recently implicated in the hereditary hyperparathyroidism–jaw tumor syndrome, parathyroid cancer, and a subset of kindreds with familial isolated hyperparathyroidism. Human parafibromin binds to RNA polymerase II as part of a PAF1 t...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582266/ https://ncbi.nlm.nih.gov/pubmed/18987311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710725105 |
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