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Role for β-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions

We used the model nematode Caenorhabditis elegans infected with the human pathogen Staphylococcus aureus to identify components of epithelial immunity. Transcriptional profiling and reverse genetic analysis revealed that mutation of the C. elegans β-catenin homolog bar-1 or the downstream homeobox g...

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Autori principali: Irazoqui, Javier E., Ng, Aylwin, Xavier, Ramnik J., Ausubel, Frederick M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582251/
https://ncbi.nlm.nih.gov/pubmed/18981407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809527105
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