Effect of anti-CD52 antibody alemtuzumab on ex-vivo culture of umbilical cord blood stem cells

BACKGROUND: Excessive maturation of hematopoietic cells leads to a reduction of long-term proliferative capability during cord blood (CB) expansion. In this study, we report the effects of anit-CD52 (Alemtuzumab, Campath) on both short- and long-term ex vivo expansion of CB hematopoietic stem cells...

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Detalhes bibliográficos
Main Authors: Lim, Che K, Sun, Li, Feng, Qi, Law, Ping, Chua, Wei T, Lim, Shy N, Hwang, William YK
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582233/
https://ncbi.nlm.nih.gov/pubmed/18947412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-1-19
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