Endogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation

Human SNM1B/Apollo is involved in the cellular response to DNA-damage, however, its precise role is unknown. Recent reports have implicated hSNM1B in the protection of telomeres. We have found hSNM1B to interact with TRF2, a protein which functions in telomere protection and in an early response to...

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Autori principali: Demuth, Ilja, Bradshaw, Paul S., Lindner, Anika, Anders, Marco, Heinrich, Stefanie, Kallenbach, Julia, Schmelz, Karin, Digweed, Martin, Meyn, M. Stephen, Concannon, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582150/
https://ncbi.nlm.nih.gov/pubmed/18468965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.020
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