CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy

CD20 is expressed in approximately one- half of pediatric acute lymphoblastic leukemia (ALL) cases with B-cell precursor (BCP) origin. We observed that it is occasionally up-regulated during treatment. To understand the impact of this on the potential effectiveness of anti-CD20 immunotherapy, we stu...

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Autors principals: Dworzak, Michael N., Schumich, Angela, Printz, Dieter, Pötschger, Ulrike, Husak, Zvenyslava, Attarbaschi, Andishe, Basso, Giuseppe, Gaipa, Giuseppe, Ratei, Richard, Mann, Georg, Gadner, Helmut
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581996/
https://ncbi.nlm.nih.gov/pubmed/18780832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-164129
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