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Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children

Plasma levels of tumor necrosis factor-α (TNF-α) are significantly raised in malaria infection and TNF-α is thought to inhibit intestinal iron absorption and macrophage iron release. This study investigated putative functional single nucleotide polymorphisms (SNPs) and haplotypes across the major hi...

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Bibliografiska uppgifter
Huvudupphovsmän: Atkinson, Sarah H., Rockett, Kirk A., Morgan, Gareth, Bejon, Philip A., Sirugo, Giorgio, O'Connell, Maria A., Hanchard, Neil, Kwiatkowski, Dominic P., Prentice, Andrew M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581977/
https://ncbi.nlm.nih.gov/pubmed/18716131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-162008
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