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A Simple Polymerase Chain Reaction-Based Method for the Construction of Recombinase-Mediated Cassette Exchange Donor Vectors

Here we describe a simple method for generating donor vectors suitable for targeted transgenesis via recombinase-mediated cassette exchange (RMCE) using the ΦC31 integrase. This PCR-based strategy employs small attB “tails” on the primers used to amplify a sequence of interest, permitting the rapid...

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Detalhes bibliográficos
Main Authors: Bateman, Jack R., Wu, C.-ting
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581973/
https://ncbi.nlm.nih.gov/pubmed/18791223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.094508
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