The Hyphal-Associated Adhesin and Invasin Als3 of Candida albicans Mediates Iron Acquisition from Host Ferritin

Iron sequestration by host iron-binding proteins is an important mechanism of resistance to microbial infections. Inside oral epithelial cells, iron is stored within ferritin, and is therefore not usually accessible to pathogenic microbes. We observed that the ferritin concentration within oral epit...

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Main Authors: Almeida, Ricardo S., Brunke, Sascha, Albrecht, Antje, Thewes, Sascha, Laue, Michael, Edwards, John E., Filler, Scott G., Hube, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581891/
https://ncbi.nlm.nih.gov/pubmed/19023418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000217
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