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Functional evidence that the Ser-195 residue of staphylococcal exfoliative toxin A is essential for biological activity.

The substitution of the serine 195 residue of staphylococcal exfoliative toxin A by a cysteine residue led to a biologically inactive protein. This result is consistent with the hypothesis that exfoliative toxin A could be a protease or a lipase. However, no protease or lipase activity was detected...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Prévost, G, Rifai, S, Chaix, M L, Piémont, Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1908832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.9.3337-3339.1991
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