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Local delivery of osteoprotegerin inhibits mechanically mediated bone modeling in orthodontic tooth movement

INTRODUCTION: The RANKL-OPG axis is a key regulator of osteoclastogenesis and bone turnover activity. Its contribution to bone resorption under altered mechanical states, however, has not been fully elucidated. Here we examined the role of OPG in regulating mechanically induced bone modeling in a ra...

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Autors principals: Dunn, Matthew D., Park, Chan Ho, Kostenuik, Paul J., Kapila, Sunil, Giannobile, William V.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581749/
https://ncbi.nlm.nih.gov/pubmed/17588510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2007.04.194
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