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Staphylococcal Toxic Shock Syndrome Toxin-1 Induces the Translocation and Secretion of High Mobility Group-1 Protein from Both Activated T Cells and Monocytes
High mobility group box-1 (HMGB-1) is a DNA-binding protein secreted by activated monocytes and has been identified as a key late mediator of endotoxic shock. We investigated the regulation of HMGB-1 in human peripheral blood mononuclear cells (PBMCs) following stimulation with the staphylococcal su...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
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Hindawi Publishing Corporation
2008
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581724/ https://ncbi.nlm.nih.gov/pubmed/19009026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/512196 |
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