Staphylococcal Toxic Shock Syndrome Toxin-1 Induces the Translocation and Secretion of High Mobility Group-1 Protein from Both Activated T Cells and Monocytes

High mobility group box-1 (HMGB-1) is a DNA-binding protein secreted by activated monocytes and has been identified as a key late mediator of endotoxic shock. We investigated the regulation of HMGB-1 in human peripheral blood mononuclear cells (PBMCs) following stimulation with the staphylococcal su...

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Autores principales: Kalyan, Shirin, Chow, Anthony W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581724/
https://ncbi.nlm.nih.gov/pubmed/19009026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/512196
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