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Identification of subregions of Bordetella pertussis filamentous hemagglutinin that stimulate human T-cell responses.

Filamentous hemagglutinin (FHA), a 220-kDa protein that mediates the adhesion of Bordetella pertussis to eukaryotic cells, is a component of acellular vaccines against whooping cough. To identify the subregions of FHA that are immunogenic for T cells, 16 human T-cell clones were raised against purif...

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Udgivet i:Infect Immun
Principais autores: Di Tommaso, A, Domenighini, M, Bugnoli, M, Tagliabue, A, Rappuoli, R, De Magistris, M T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1715327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.9.3313-3315.1991
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