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Pathogenicity of Candida albicans auxotrophic mutants in experimental infections.

Auxotrophic and prototrophic control strain pairs of Candida albicans constructed by molecular biology methodologies were evaluated for pathogenicity in a systemic mouse model. Mutants that were auxotrophic for adenine, uracil, and heme each showed a lowered level of pathogenicity relative to contro...

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Detalhes bibliográficos
Main Authors: Kirsch, D R, Whitney, R R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC258168/
https://ncbi.nlm.nih.gov/pubmed/1879944
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