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Pathogenicity of Candida albicans auxotrophic mutants in experimental infections.
Auxotrophic and prototrophic control strain pairs of Candida albicans constructed by molecular biology methodologies were evaluated for pathogenicity in a systemic mouse model. Mutants that were auxotrophic for adenine, uracil, and heme each showed a lowered level of pathogenicity relative to contro...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC258168/ https://ncbi.nlm.nih.gov/pubmed/1879944 |
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