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OTK18 levels in plasma and cerebrospinal fluid correlate with viral load and CD8 T-cells in normal and AIDS patients

BACKGROUND: OTK18 is a C(2)H(2) type zinc finger protein expressed by human macrophages following HIV infection. OTK18 possesses antiretroviral activity and its processing products accumulate in the cytoplasm of perivascular brain macrophages in advanced HIV encephalitis cases. OBJECTIVES: Since the...

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Bibliographische Detailangaben
Hauptverfasser: Buescher, James L., Duan, Fenghai, Sun, Junfeng, Price, Richard W., Ikezu, Tsuneya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581637/
https://ncbi.nlm.nih.gov/pubmed/18773297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-008-9125-3
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