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Type I Collagen Is a Genetic Modifier of Matrix Metalloproteinase 2 in Murine Skeletal Development

Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone loss. Mmp2(-/-) mice have only mild aspects of these abnormalities, suggesting that MMP2 function is redunda...

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Autores principales: Egeblad, Mikala, Shen, H.-C. Jennifer, Behonick, Danielle J., Wilmes, Lisa, Eichten, Alexandra, Korets, Lidiya V., Kheradmand, Farrah, Werb, Zena, Coussens, Lisa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581616/
https://ncbi.nlm.nih.gov/pubmed/17440987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21159
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