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Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

Protease-activated receptor 2 (PAR2) is expressed by vascular endothelial cells and other cells in which its function and physiological activator(s) are unknown. Unlike PAR1, PAR3, and PAR4, PAR2 is not activatable by thrombin. Coagulation factors VIIa (FVIIa) and Xa (FXa) are proteases that act ups...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Camerer, Eric, Huang, Wei, Coughlin, Shaun R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.10.5255
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