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MEKK4 sequesters RIP2 to dictate signal specificity downstream of the Crohn’s Disease Susceptibility Protein, NOD2
The Crohn’s Disease-susceptibility protein, NOD2, coordinates signaling responses upon intracellular exposure to bacteria (1-6). While NOD2 is known to activate NFκB, little is known about the molecular mechanisms by which NOD2 coordinates functionally separate signaling pathways such as NFκB, JNK a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581469/ https://ncbi.nlm.nih.gov/pubmed/18775659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.07.084 |
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