Inhibition of leukotriene biosynthesis abrogates the host control of Mycobacterium tuberculosis

Leukotrienes produced from arachidonic acid by the action of 5-lipoxygenase (5-LO) are classical mediators of inflammatory responses. Recently, it has been demonstrated that leukotrienes also play an important role in host defense against microorganisms. In vitro studies have shown that leukotrienes...

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Main Authors: Peres, Camila M., de Paula, Lúcia, Medeiros, Alexandra I., Sorgi, Carlos A., Soares, Edson G., Carlos, Daniela, Peters-Golden, Marc, Silva, Célio L., Faccioli, Lúcia H.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581410/
https://ncbi.nlm.nih.gov/pubmed/17347013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2007.01.006
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