Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies.

Microspheres composed of biocompatible, biodegradable poly(DL-lactide-co-glycolide) (DL-PLG) and staphylococcal enterotoxin B (SEB) toxoid were evaluated as a vaccine delivery system when subcutaneously injected into mice. As measured by circulating immunoglobulin G (IgG) antitoxin titers, the deliv...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Eldridge, J H, Staas, J K, Meulbroek, J A, Tice, T R, Gilley, R M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258122/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1879922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.9.2978-2986.1991
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