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Proteomic Identification of In Vivo Substrates for Matrix Metalloproteinases 2 and 9 Reveals a Mechanism for Resolution of Inflammation

Clearance of allergic inflammatory cells from the lung through matrix metalloproteinases (MMPs) is necessary to prevent lethal asphyxiation, but mechanistic insight into this essential homeostatic process is lacking. In this study, we have used a proteomics approach to determine how MMPs promote egr...

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Bibliographic Details
Main Authors: Greenlee, Kendra J., Corry, David B., Engler, David A., Matsunami, Risë K., Tessier, Philippe, Cook, Richard G., Werb, Zena, Kheradmand, Farrah
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580826/
https://ncbi.nlm.nih.gov/pubmed/17082650
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