Human Mycobacterium tuberculosis-reactive CD4+ T-cell clones: heterogeneity in antigen recognition, cytokine production, and cytotoxicity for mononuclear phagocytes.

CD4+ T cells regulate the protective immune response which follows exposure to Mycobacterium tuberculosis by activating macrophages through the cytokines the CD4+ T cells secrete. In addition CD4+ T cells have been shown to be directly cytotoxic for antigen-pulsed mononuclear phagocytes (monocytes-m...

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Vydáno v:	Infect Immun
Hlavní autoři:	Boom, W H, Wallis, R S, Chervenak, K A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1713198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.8.2737-2743.1991
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