Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets.

A mutant strain of Helicobacter pylori with weak urease activity was created by using N-methyl-N'-nitro-N-nitrosoguanidine. The urease activity of the mutant (0.036 +/- 0.009 nmol of urea per micrograms of bacterial protein per min) was 0.4% of that of the parental strain (8.20 +/- 2.30 nmol of urea...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Eaton, K A, Brooks, C L, Morgan, D R, Krakowka, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2050411/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.7.2470-2475.1991
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