TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice

PURPOSE: The ability of brain-derived neurotrophic factor (BDNF) to attenuate secondary damage and influence behavioral outcome after experimental traumatic brain injury (TBI) remains controversial. Because TBI can result in decreased expression of the trkB receptor, thereby preventing BDNF from exe...

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Main Authors: Conte, Valeria, Raghupathi, Ramesh, Watson, Deborah J., Fujimoto, Scott, Royo, Nicolas C., Marklund, Niklas, Stocchetti, Nino, McIntosh, Tracy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580053/
https://ncbi.nlm.nih.gov/pubmed/18431005
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