Expression and immunogenicity of a streptococcal M protein epitope inserted in Salmonella flagellin.

A synthetic 48-bp oligonucleotide specifying the N-terminal 15 amino acids of M protein of Streptococcus pyogenes type 5 (plus a CTA codon, to terminate translation of genes with the insert in reverse orientation) was inserted by blunt-end ligation at the site of the 48-bp EcoRV deletion in the Salm...

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Bibliographic Details
Main Authors: Newton, S M, Kotb, M, Poirier, T P, Stocker, B A, Beachey, E H
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC257981/
https://ncbi.nlm.nih.gov/pubmed/2037377
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