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Susceptibility of beige mutant mice to candidiasis may be linked to a defect in granulocyte production by bone marrow stem cells.

The beige mutation in mice has a pervasive effect on mechanisms of host resistance to infectious agents. Best characterized are defects in granulocyte chemotaxis and phagocytosis, which are associated with increased susceptibility to bacteria, and a deficiency in the levels of natural killer (NK) ce...

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Pubblicato in:Infect Immun
Autori principali: Ashman, R B, Papadimitriou, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257978/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2037375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.6.2140-2146.1991
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