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The Interleukin-1 Receptor Associated Kinase 1 contributes to the regulation of NFAT

IRAK-1 is a critical modulator regulating innate immunity signaling processes. However, the physiological substrates for IRAK-1 remain poorly defined. In this report, we have demonstrated that IRAK-1 is a kinase responsible for the constitutive phosphorylation and inactivation of the Nuclear Factor...

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Autors principals: Wang, Dongmei, Fasciano, Stephan, Gan, Lu, Li, Liwu
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579773/
https://ncbi.nlm.nih.gov/pubmed/18691762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.06.023
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