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Ciprofloxacin-induced G(2) arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation

Drugs developed for the treatment of conditions other than neoplasia can also show promise as potential antitumor agents. The fluoroquinolone antibiotic ciprofloxacin (CPFX) is known to modulate cycle cell progression and apoptosis in cancer cells, and is thought to induce DNA double-strand breaks (...

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Bibliografske podrobnosti
Main Authors: Smart, Daniel J., Halicka, H. Dorota, Traganos, Frank, Darzynkiewicz, Zbigniew, Williams, Gary M.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579770/
https://ncbi.nlm.nih.gov/pubmed/18059176
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