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Gene set enrichment analysis using linear models and diagnostics

Motivation: Gene-set enrichment analysis (GSEA) can be greatly enhanced by linear model (regression) diagnostic techniques. Diagnostics can be used to identify outlying or influential samples, and also to evaluate model fit and explore model expansion. Results: We demonstrate this methodology on an...

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Main Authors: Oron, Assaf P., Jiang, Zhen, Gentleman, Robert
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579710/
https://ncbi.nlm.nih.gov/pubmed/18790795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn465
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