Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma

Carbonic anhydrase 9 (CA9) is a protein to be upregulated under exposure to hypoxic conditions. Hypoxic conditions are known to be associated with resistance to chemotherapy and radiotherapy, and with poor cancer prognosis. We examined CA9 expression in surgical specimens from oesophageal squamous c...

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Autors principals: Tanaka, N, Kato, H, Inose, T, Kimura, H, Faried, A, Sohda, M, Nakajima, M, Fukai, Y, Miyazaki, T, Masuda, N, Fukuchi, M, Kuwano, H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579701/
https://ncbi.nlm.nih.gov/pubmed/18841153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604719
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